Alzheimer's disease (A.D), also known simply as Alzheimer's, is a neurodegenerative disease (a condition in which cells of the brain and spinal cord are lost. It affects people over age 65. Approximately 24 million people worldwide have dementia of which the majority (~60%) is due to Alzheimer's.
Clinical signs of this disease are characterized by progressive cognitive deterioration, together with declining activities of daily living and by behavioral changes. It is the most common type of dementia (the progressive decline in cognitive function). Some changes in the brain cells can only be discovered at autopsy and help to confirm the clinical diagnosis. Medications can help reduce the symptoms of the disease, but they cannot change the course of the underlying pathology.
Although the cause of Alzheimer's is unknown, genetic factors are suspected.
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